Pelvic Mass Associated With Raised CA 125 For Benign Condition: A Case Report

Background:
Elevated levels of CA 125 with clinical evidence of significant weight loss and associated pelvic mass is highly suggestive of ovarian malignancy, this creates a diagnostic dilemma with the knowledge that several benign pelvic conditions may present with same findings.
Conclusion:
The presence of a pelvic mass with a raised CA 125 of 1450 units/ml, lymphadenopathy and other associated suspicious features on CT scan suggested an ovarian malignancy. A subsequent fall of CA 125 to 23 units/ml pointed to an inflammatory condition as was found intraoperatively. Raised CA 125 levels can be misleading, as illustrated in this case, a differential diagnosis of inflammatory pelvic condition should always be considered in young patients. While CT and CA 125 aids in diagnosis they should not completely supplant the need to rely on clinical history and examination findings.

Increasing the Effectiveness of Referral of Ovarian Masses From Cancer Unit to Cancer Center by Using a Higher Referral Value of the Risk of Malig.........

Increasing the Effectiveness of Referral of Ovarian Masses From Cancer Unit to Cancer Center by Using a Higher Referral Value of the Risk of Malignancy Index
Hypothesis

Higher risk of malignancy index (RMI) with multidisciplinary approach will reduce the number of referrals of ovarian masses, thus reducing the stress for patients and workload at the cancer center.
Conclusions: A higher RMI with multidisciplinary approach to refer patients with pelvic masses has the potential to reduce the numbers of benign cases, thus reducing stress for patients and reducing workload at centers.

Abstract and full free text available: Pelvic mass associated with raised CA 125 for benign condition: A case report

Note: this paper also discusses differences between ultrasound/CT/MRI

Abstract
Background
Raised CA 125 with associated pelvic mass is highly suggestive of ovarian malignancy, but there are various other benign conditions that can be associated with pelvic mass and a raised CA 125.
Case presentation
We present a case of 19 year old