Showing posts with label pseudomyxoma peritonei. Show all posts
Showing posts with label pseudomyxoma peritonei. Show all posts
Tuesday, May 22, 2012
Editorial: Pseudomyxoma Peritonei: More Questions Than Answers (appendix/ovarian
JCO: Pseudomyxoma Peritonei: More QuestionsThan Answers
"Chances are, if you ask most physicians and surgeons about
pseudomyxoma peritonei (PMP), they will respond with more questions
than answers. The confusion that surrounds PMPis not surprising
because the origin, pathology, treatment, prognosis, and very
definition of PMP are still under debate. PMP is a clinical syndrome
that is characterized by mucinous ascites that result from rupture of a
mucin-producing neoplasm, typically of appendiceal origin....."
"...The appendix is the primary cause of PMP; the ovaries are typically
only secondarily involved...."
add your opinions
appendix
,
ascites
,
mucin
,
mucinous
,
pseudomyxoma peritonei
Wednesday, April 04, 2012
abstract: Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer - Segelman - 2012 - British Journal of Surgery - Wiley Online Library
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer - Segelman - 2012 - British Journal of Surgery
Abstract
Background:
This
was a population-based cohort study to determine the incidence,
prevalence and risk factors for peritoneal carcinomatosis (PC) from
colorectal cancer.
Methods:
Prospectively
collected data were obtained from the Regional Quality Registry. The
Cox proportional hazards regression model was used for multivariable
analysis of clinicopathological factors to determine independent
predictors of PC.
Results:
All
11 124 patients with colorectal cancer in Stockholm County during
1995–2007 were included and followed until 2010. In total, 924 patients
(8·3 per cent) had synchronous or metachronous PC. PC was the first and
only localization of metastases in 535 patients (4·8 per cent). The
prevalence of synchronous PC was 4·3 per cent (477 of 11 124). The
cumulative incidence of metachronous PC was 4·2 per cent (447 of 10
646). Independent predictors for metachronous PC were colonic cancer
(hazard ratio (HR) 1·77, 95 per cent confidence interval 1·31 to 2·39; P = 0·002 for right-sided colonic cancer), advanced tumour (T) status (HR 9·98, 3·10 to 32·11; P < 0·001 for T4), advanced node (N) status (HR 7·41, 4·78 to 11·51; P < 0·001 for N2 with fewer than 12 lymph nodes examined), emergency surgery (HR 2·11, 1·66 to 2·69; P < 0·001) and non-radical resection of the primary tumour (HR 2·75, 2·10 to 3·61; P < 0·001 for R2 resection). Patients aged > 70 years had a decreased risk of metachronous PC (HR 0·69, 0·55 to 0·87; P = 0·003).
Conclusion:
PC
is common in patients with colorectal cancer and is associated with
identifiable risk factors.
add your opinions
appendix
,
colon
,
colorectal
,
gall bladder
,
mesothelioma
,
ovarian
,
pancreas
,
peritoneal carcinomatosis
,
pseudomyxoma peritonei
,
rectal
,
small bowel
,
stomach
Subscribe to:
Posts
(
Atom
)