OVARIAN CANCER and US: sequence

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Showing posts with label sequence. Show all posts
Showing posts with label sequence. Show all posts

Friday, February 19, 2010

PLoS Genetics: Use of DNA–Damaging Agents and RNA Pooling to Assess Expression Profiles Associated with BRCA1 and BRCA2 Mutation Status in Familial Breast Cancer Patients



definition: heterogeneous - the quality of being diverse and not comparable in kind

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"A large number of rare sequence variants of unknown clinical significance have been identified in the breast cancer susceptibility genes, BRCA1 and BRCA2. Laboratory
methods to identify which of these variants are mutations would have utility for counseling and clinical decision making when identified in patients with a family history of
breast cancer."