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Showing posts with label vrca. Show all posts
Showing posts with label vrca. Show all posts

Wednesday, April 07, 2010

Validation of the pedigree assessment tool (PAT) in families with BRCA1 and BRCA2 mutations



CONCLUSIONS: In overall performance, the PAT is at least comparable to the Myriad II and Penn II models in screening women appropriate for genetic referral. Simplicity and identification of families with non-BRCA hereditary BC syndromes suggest that the PAT is better suited for BC risk screening.