abstract: Treatment of Ovarian Cancer in Young Women : Clinical Obstetrics and Gynecology

Clinical Obstetrics & Gynecology:

March 2012 - Volume 55 - Issue 1 - p 65–74

doi: 10.1097/GRF.0b013e318248045b

Ovarian Cancer

Treatment of Ovarian Cancer in Young Women

GERSHENSON, DAVID M. MD

Abstract

Ovarian cancer accounts for approximately 22,000 cases annually in the United States. 

Although the vast majority of ovarian cancers occur in postmenopausal women and are of advanced stage, a significant subset occurs in young women. 

Among those subtypes having a predisposition for young women are malignant ovarian germ cell tumors, sex cord-stromal ovarian tumors, and tumors of low malignant potential. 

However, invasive epithelial ovarian cancers may also occur in young women, particularly the subtypes of low-grade serous carcinoma and mucinous carcinoma. This article details the diagnosis and optimal treatment of ovarian cancers subtypes in young women.

abstract: Pregnant woman with an extremely small uterus due to pelvic irradiation in childhood (very sad)

Pregnant woman with an extremely small uterus due to pelvic irradiation in childhood:

Abstract

"A female cancer survivor, having suffered malignant lymphoma during childhood and received radio- and chemotherapy, became pregnant. Her uterus was extremely small and in the 22nd week of gestation, acute uterine contractions occurred, leading to preterm delivery and resulting in the death of the infant. Pelvic irradiation in childhood was considered to have caused a small uterus and thus brought on preterm delivery. The younger the patient, the more vulnerable the uterus is to irradiation. The exposure dose to the uterus in pediatric cancer patients should therefore be reduced, especially in younger patients. The cooperation of pediatric cancer specialists and obstetricians is necessary to preserve the future fertility of female cancer survivors."

Young Women Diagnosed With BRCA Genes -- What Should They Do?

Analysis of 21 cases of epithelial ovarian malignancies in women aged below 30 years

Fertility-sparing surgery in young women with invasive epithelial ovarian cancer.

Note: this study also discusses tumour rupture/survival; the abstract does not include specific cell types, however, clear cell can be possibly presumed given the research data on Japanese women with clear cell ovarian cancer.