Review: Opportunistic salpingectomy for ovarian cancer prevention

Open access

 In summary, opportunistic salpingectomy is a safe intervention in the short term, when done concurrently with hysterectomy or instead of tubal ligation. It has the potential to reduce the incidence and mortality from ovarian cancer, and it may have an important role as a temporizing measure in high-risk women with BRCA mutations who are unwilling to undergo standard risk reducing surgery (bilateral salpingo-oophorectomy) at an early age. It will still be essential to evaluate long-term safety and efficacy outcomes to support the ongoing use of this intervention in the general population as well as the high-risk setting.