Showing posts with label A4. Show all posts
Showing posts with label A4. Show all posts
Saturday, February 05, 2011
abstract: Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer
Note: searching blog for A4 will provide further research specific to clear cell/A4
CONCLUSIONS: The addition of CA4P to paclitaxel and carboplatin is well tolerated and appears to produce a higher response rate in this patient population than if the chemotherapy was given without CA4P. A planned randomised trial will test this hypothesis.
add your opinions
A4
,
CA4P
,
clear cell
,
phosphate
Wednesday, August 04, 2010
Targeting annexin A4 to counteract chemoresistance in clear cell carcinoma of the ovary
Take home message: Annexin A4 enhances cancer cell chemoresistance and is overexpressed in tumors of patients with ovarian CCC. Targeting of annexin A4 may represent a future strategy to counteract resistance to chemotherapy in ovarian CCC.
add your opinions
A4
,
chemoresistance
,
chemoresistant
,
clear cell ovarian
,
targeted therapy
Tuesday, April 13, 2010
A Phase Ib trial of CA4P (combretastatin A-4 phosphate), carboplatin, and paclitaxel in patients with advanced cancer
Conclusion:
The combination of CA4P with carboplatin and paclitaxel was well tolerated in the majority of patients with adequate premedication and had antitumour activity in patients who were heavily pretreated.
add your opinions
A4
,
CA4P
,
Carboplatin
,
Taxol
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