Diffusion-weighted Imaging Study in Cancer of the Ovary - Full Text View - ClinicalTrials.gov
Diffusion-weighted Imaging Study in Cancer of the Ovary (DISCOVAR)
This study is not yet open for participant recruitment.
Verified March 2012 by Institute of Cancer Research, United Kingdom
First Received on November 18, 2011.
Last Updated on March 30, 2012
History of Changes
| Sponsor: | Institute of Cancer Research, United Kingdom |
|---|---|
| Collaborators: | Cancer Research UK Royal Marsden NHS Foundation Trust Cambridge University Hospitals NHS Foundation Trust Imperial College Healthcare NHS Trust Northumbria Healthcare NHS Foundation Trust |
| Information provided by (Responsible Party): | NdeSouza, Institute of Cancer Research, United Kingdom |
| ClinicalTrials.gov Identifier: | NCT01505829 |
Purpose
This
project seeks to develop a quantitative imaging biomarker for evaluating
and monitoring treatment response in ovarian cancer metastases and
assess its potential in monitoring treatment response. This will involve
standardising DW-MRI for the abdomen and pelvis across multiple centres
and platforms, assessing reproducibility of the measurement in patients
planned for neoadjuvant chemotherapy and assessing its utility as an
early response biomarker in patients with platinum-sensitive relapse due
to receive therapy with carboplatin. Scanning measurements will be
correlated with histopathological markers in tumour samples in order to
link the biomarker with response mechanisms.
| Condition |
|---|
| Ovarian Cancer Peritoneal Metastases |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Assessing Treatment Response of Peritoneal Metastases in Ovarian Cancer Using Diffusion Weighted Magnetic Resonance Imaging. |
