Showing posts with label WBRT. Show all posts
Showing posts with label WBRT. Show all posts
Monday, May 28, 2012
Neurocognitive function impairment after whole brain radiotherapy for brain metastases: actual assessment
Neurocognitive function impairment after wholebrain radiotherapy for brain metastases: actual assessment
Conclusion
......The results of this review will enable physicians to inform
patients about benefits and risks of these two treatment options.
Friday, January 13, 2012
abstract: Whole-brain radiation therapy of brain metastasis.
Source
Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Princess Margaret Hospital, University of Toronto, Toronto, Ont., Canada.
Abstract
The purpose of this report was to review the role of whole brain radiotherapy (WBRT) in the management of brain metastases. In particular, we review the role of WBRT as a prophylactic therapy, and the role of surgery and stereotactic radiosurgery (SRS) with respect to WBRT, by discussing the relevant randomized controlled trials. WBRT is associated with toxicities and this may influence the decision to use WBRT and, therefore, we review both the acute side effects of WBRT and the moreserious late side effects of neurocognitive impairment and leukoencephalopathy. As patients are living longer with brain metastases the role of WBRT is moving forward; however, using modern radiation technology we may be able to reduce the morbidity of this therapy. We present an extreme case of re-re-treatment WBRT with hippocampal sparing and simultaneous integrated boosts to multiple lesions as one of the future directions under evaluation.
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