Showing posts with label brain metastases. Show all posts
Showing posts with label brain metastases. Show all posts
Monday, May 28, 2012
Neurocognitive function impairment after whole brain radiotherapy for brain metastases: actual assessment
Neurocognitive function impairment after wholebrain radiotherapy for brain metastases: actual assessment
Conclusion
......The results of this review will enable physicians to inform
patients about benefits and risks of these two treatment options.
Thursday, May 17, 2012
Gamma knife surgery for brain metastases from ovarian cancer.
numerous tables including:
Table 1 Patient characteristics of 16 patients with 119 brain metastases
Conclusions
Brain metastases from ovarian cancer are
rare, but their incidence is increasing as patient survival has been
extended by
successful platinum-based chemotherapy and improved
imaging techniques have enabled the identification of smaller lesions.
In our study, the median survival from brain metastases
was 12.5 months, and the local control rate was 86.4 %. The KPS and
total volume of brain metastases were important factors
predictive of survival. Our results suggest that GKS is an acceptable
therapy for brain metastases from ovarian cancer.
Conflicts of interest
None.
Open Access
Sunday, April 01, 2012
open access: Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
Cone-beam computed tomography in hypofractionatedstereotactic radiotherapy for brain metastases
Conclusions
Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment
position.
Friday, January 13, 2012
abstract: Whole-brain radiation therapy of brain metastasis.
Source
Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Princess Margaret Hospital, University of Toronto, Toronto, Ont., Canada.
Abstract
The purpose of this report was to review the role of whole brain radiotherapy (WBRT) in the management of brain metastases. In particular, we review the role of WBRT as a prophylactic therapy, and the role of surgery and stereotactic radiosurgery (SRS) with respect to WBRT, by discussing the relevant randomized controlled trials. WBRT is associated with toxicities and this may influence the decision to use WBRT and, therefore, we review both the acute side effects of WBRT and the moreserious late side effects of neurocognitive impairment and leukoencephalopathy. As patients are living longer with brain metastases the role of WBRT is moving forward; however, using modern radiation technology we may be able to reduce the morbidity of this therapy. We present an extreme case of re-re-treatment WBRT with hippocampal sparing and simultaneous integrated boosts to multiple lesions as one of the future directions under evaluation.Wednesday, January 04, 2012
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