Showing posts with label coffee. Show all posts
Showing posts with label coffee. Show all posts
Monday, May 21, 2012
Thursday, April 26, 2012
paywalled: Coffee intake and breast cancer risk in the NIH-AARP diet and health study cohort - Gierach - 2011 - International Journal of Cancer - Wiley Online Library
Coffee intake and breast cancer risk in the NIH-AARP diet and health study cohort - International Journal of Cancer
"These findings from a large prospective cohort do not support a role of coffee intake in breast carcinogenesis."
paywalled: Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis
Blogger's Note/Opinion: as per abstract, to date and studies over decades, have not found a link between coffee/tea/ovarian cancer risk - so, the question is this: how many more studies will it take to finally put this issue to rest? Unless there are novel (new) findings then we need to move forward.
Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis
Abstract
Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of
coffee and tea consumption on the risk of epithelial ovarian cancer (EOC).
Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes,
tea intakes, or both are associated with the risk of EOC.
Design: All women participating in the EPIC (n
= 330,849) were included in this study. Data on coffee and tea
consumption were collected through validated food-frequency
questionnaires at baseline. HRs and 95% CIs were
estimated by using Cox proportional hazards models. Furthermore, we
performed
an updated meta-analysis of all previous
prospective studies until April 2011 by comparing the highest and lowest
coffee-
and tea-consumption categories as well as by using
dose-response random-effects meta-regression analyses.
Results: During a median
follow-up of 11.7 y, 1244 women developed EOC. No association was
observed between the risk of EOC and coffee
consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the
top quintile compared with no intake] or tea consumption [HR: 1.07 (95%
CI: 0.78, 1.45) for the top quintile compared with
no intake]. This lack of association between coffee and tea intake and
EOC risk was confirmed by the results of our
meta-analysis.
Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and
risk of ovarian cancer.
Sunday, March 25, 2012
abstract: Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis - EU/UK
Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis
Abstract
Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of
coffee and tea consumption on the risk of epithelial ovarian cancer (EOC).
Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes,
tea intakes, or both are associated with the risk of EOC.
Design: All women participating in the EPIC (n
= 330,849) were included in this study. Data on coffee and tea
consumption were collected through validated food-frequency
questionnaires at baseline. HRs and 95% CIs were
estimated by using Cox proportional hazards models. Furthermore, we
performed
an updated meta-analysis of all previous
prospective studies until April 2011 by comparing the highest and lowest
coffee-
and tea-consumption categories as well as by using
dose-response random-effects meta-regression analyses.
Results: During a median
follow-up of 11.7 y, 1244 women developed EOC. No association was
observed between the risk of EOC and coffee
consumption for the
top quintile compared with no intake] or tea consumption for the top quintile compared with
no intake]. This lack of association between coffee and tea intake and
EOC risk was confirmed by the results of our
meta-analysis.
Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and
risk of ovarian cancer.
Sunday, November 14, 2010
Monday, June 28, 2010
Monday, April 05, 2010
Epidemiologic evidence on coffee and cancer
Nutr Cancer. 2010 Apr;62(3):271-83.
Epidemiologic evidence on coffee and cancer.
Arab L.
David Geffen School of Medicine, University of California, Los Angeles, USA.
Coffee consumption is a major and frequent dietary exposure in diverse cultures around the globe whose safety has been questioned. A substantial body of epidemiologic evidence, consisting of over 500 papers relating the consumption of coffee to cancer of various sites, has accumulated to date. Numerous individual, site-specific meta analyses have been undertaken at various times. However, there is no comprehensive, up-to-date overview of the entirety of the knowledge base. To address this need, this review summarized the findings of the meta analyses and recent papers on site-specific human cancers among coffee consumers. For hepatocellular and endometrial cancers, there appears to be a strong and consistent protective association; for colorectal cancer, the direction of association is borderline protective. There appears to be no association with breast, pancreatic, kidney, ovarian, prostate, or gastric cancer. Risk of bladder cancer appears to be associated with heavy coffee consumption in some populations and among men. The associations with childhood leukemia and mother's consumption of coffee were ambiguous-with some suggestion of risk at high levels of daily consumption.
PMID: 20358464 [PubMed - in process]
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