Blogger's Note/Opinion: as per abstract, to date and studies over decades, have not found a link between coffee/tea/ovarian cancer risk - so, the question is this: how many more studies will it take to finally put this issue to rest? Unless there are novel (new) findings then we need to move forward.
Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis
Abstract
Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of
coffee and tea consumption on the risk of epithelial ovarian cancer (EOC).
Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes,
tea intakes, or both are associated with the risk of EOC.
Design: All women participating in the EPIC (n
= 330,849) were included in this study. Data on coffee and tea
consumption were collected through validated food-frequency
questionnaires at baseline. HRs and 95% CIs were
estimated by using Cox proportional hazards models. Furthermore, we
performed
an updated meta-analysis of all previous
prospective studies until April 2011 by comparing the highest and lowest
coffee-
and tea-consumption categories as well as by using
dose-response random-effects meta-regression analyses.
Results: During a median
follow-up of 11.7 y, 1244 women developed EOC. No association was
observed between the risk of EOC and coffee
consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the
top quintile compared with no intake] or tea consumption [HR: 1.07 (95%
CI: 0.78, 1.45) for the top quintile compared with
no intake]. This lack of association between coffee and tea intake and
EOC risk was confirmed by the results of our
meta-analysis.
Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and
risk of ovarian cancer.
