Structural and Functional Imaging and Cognitive Functions in Ovarian Cancer - Full Text View - ClinicalTrials.gov (clinical trials)

Structural and Functional Imaging and Cognitive Functions in Ovarian Cancer - Full Text View - ClinicalTrials.gov

This study is currently recruiting participants.

Verified May 2012 by Memorial Sloan-Kettering Cancer Center

First Received on April 30, 2012.   Last Updated on May 2, 2012   History of Changes

Sponsor:	Memorial Sloan-Kettering Cancer Center
Collaborator:	Weill Medical College of Cornell University
Information provided by (Responsible Party):	Memorial Sloan-Kettering Cancer Center ( Memorial Sloan-Kettering Cancer Center )
ClinicalTrials.gov Identifier:	NCT01591772

  Purpose

The purpose of this study is to learn about possible changes in brain anatomy and function, and in thinking abilities, such as memory skills, in patients with ovarian cancer who receive treatment with chemotherapy. Cancer patients treated with chemotherapy may experience changes in thinking abilities, and these may interfere with quality of life. Most of the research to date has involved patients with breast cancer, and there are no studies in women with ovarian cancer looking at at treatment-related changes in brain anatomy and function.

in research: The Cognitive Effects of Conjugated Equine Estrogens Depend on Whether Menopause Etiology Is Transitional or Surgical -- Endocrinology

Note: abstract only/$$$ full access

"Type of menopause, surgical vs. transitional, impacts cognitive outcome in women. However, whether type of menopause impacts cognitive effects of HT has not been methodically tested in women or an animal model...........That we now show surgical vs. transitional modes of menopause result in disparate cognitive effects of HT has implications for future research and treatments optimizing HT for menopausal women."