abstract/professional comments: Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial

Candidate gene association studies: successes and failures

Abstract

"Epidemiologic studies of twins indicate that 20-40% of common tumors such as breast, colorectal, and prostate cancers are inherited. However, the effect of high penetrance tumor susceptibility genes such as APC, BRCA1, BRAC2, MSH1, MLH2 and MSH6 only accounts for a small fraction of these cancers. Low to moderate penetrance tumor susceptibility genes likely account for the large remaining proportion of familial cancer risk...."

repost: Advanced ovarian carcinoma: Does a high-dose short-duration schedule of paclitaxel trump prolonged low-dose therapy? - Cancer Network

Ovarian Cancer

Oncology NEWS International. Vol. 19 No. 4
Pages: 1 2

Point / Counterpoint
"Advanced ovarian carcinoma: Does a high-dose short-duration schedule of paclitaxel trump prolonged low-dose therapy?"

Advanced ovarian carcinoma: Does a high-dose short-duration schedule of paclitaxel trump prolonged low-dose therapy? - Cancer Network

Note: This is a good discussion debating pros/cons (requires registration to view/free) - some excerpts from article:

Point / Counterpoint