Showing posts with label polymer micell nanotechnology. Show all posts
Showing posts with label polymer micell nanotechnology. Show all posts
Thursday, August 19, 2010
Journal of Ovarian Research Full free access Scope of nanotechnology in ovarian cancer therapeutics
Note: Table 1 includes cumulative toxicity and other comparisons between commonly prescribed ovarian cancer chemotherapies
Abstract
This review describes the use of polymer micelle nanotechnology based chemotherapies for ovarian cancer. While various chemotherapeutic agents can be utilized to improve the survival rate of patients with ovarian cancer, their distribution throughout the entire body results in high normal organ toxicity. Polymer micelle nanotechnology aims to improve the therapeutic efficacy of anti-cancer drugs while minimizing the side effects....... An important feature of polymer micelle nanotechnology is the small size (10-100 nm) of particles which improves circulation and enables superior accumulation of the therapeutic drugs at the tumor sites. This review provides a comprehensive evaluation of different types of polymer micelles and their implications in ovarian cancer therapeutics.
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