Showing posts with label protocol. Show all posts
Showing posts with label protocol. Show all posts
Saturday, January 23, 2010
Understanding the problem of inadequately staging of early ovarian cancer (subanalysis of ACTION trial)
CONCLUSIONS: Even in a randomised trial in which comprehensive surgical staging was strongly advised in the study protocol the majority of patients (66%) were incompletely staged. Factors relating to a lack of surgical skills attributed most to the number of incompletely staged patients, but insufficient knowledge of the tumour behaviour and routes of spread of ovarian cancer also contributed substantially to this problem. Multicentre trials recruiting patients from many institutes with small volume contribution to the study, run the risk of inadequate adherence to the study protocol.
add your opinions
clinical trials
,
incomplete
,
knowledge
,
lack of action
,
lancet oncology ovarian cancer detection study
,
multicentre
,
protocol
,
staging
,
surgery
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