Mechanism of action and toxicities of purgatives used for colonoscopy preparation

Take home message: Although generally safe and effective, colonic purgatives have both acute and permanent toxicities. The safest preparations utilize PEG combined with a balanced electrolyte solution. Limitations of this preparation center on the volume required and poor taste. Alternative formulations are now available; however, those using sodium phosphate have fallen out of favor due to a risk of renal toxicity

Read More: http://informahealthcare.com/doi/abs/10.1517/17425255.2011.542411