OVARIAN CANCER and US

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Friday, January 22, 2010

Clinical Trials Search of: Open Studies - ovarian cancer



Search of: Open Studies | ovarian cancer | Adult | updated from 01/01/2010 to 01/22/2010 - List Results - ClinicalTrials.gov

The cost-effectiveness of genetic testing strategies for Lynch Syndrome among newly diagnosed patients with colorectal cancer



"This finding provides support for a recent US recommendation to offer testing for Lynch syndrome to all newly diagnosed patients with colorectal cancer."

MRI, CT, and PET/CT for Ovarian Cancer Detection and Adnexal Lesion Characterization



"CONCLUSION. The goal of imaging in ovarian cancer detection is to expeditiously distinguish benign adnexal lesions from those requiring further pathologic evaluation for malignancy. For lesions indeterminate on ultrasound, MRI increases the specificity of imaging evaluation, thus decreasing benign resections. CT is useful in diagnosis and treatment planning of advanced cancer. Although 18F-FDG-avid ovarian lesions in postmenopausal women are considered suspicious for malignancy, PET/CT is not recommended for primary cancer detection because of high false-positive rates."

MRI of Endometriotic Cysts in Association With Ovarian Carcinoma



"CONCLUSION. Endometriotic cysts with enhanced mural nodules are not always complicated with malignancy. In elderly patients, the presence of large enhanced nodules on large endometriotic cysts is more likely to indicate malignancy."

abstract: Clinical Decision Making Using Ovarian Cancer Risk Assessment




Advances in Sonographic Detection of Ovarian Cancer: Depiction of Tumor Neovascularity With Microbubbles




Risk Assessment and Genetic Testing for Ovarian Cancer



"CONCLUSION. To offer potentially life-saving interventions for at-risk family members, we propose that every woman newly diagnosed with ovarian cancer be offered genetic testing for BRCA1 and BRCA2 genes because mutations in these genes are the strongest known predictors of ovarian cancer risk."

Ultrasound and Assessment of Ovarian Cancer Risk





New Frontiers for Ovarian Cancer Risk Evaluation: Proteomics and Contrast-Enhanced Ultrasound



abstract: Current Update on Borderline Ovarian Neoplasms



CONCLUSION. Borderline tumors are considered to be precursors of low-grade ovarian cancers. Accurate diagnosis and staging facilitate optimal patient management particularly in patients desiring to preserve fertility.

MRI in the planning of initial lumpectomy for invasive breast carcinoma: effect on ipsilateral breast tumor recurrence after breast conserving therapy



CONCLUSION: MRI evaluation of invasive carcinoma in the planning of initial lumpectomies was not associated with improved local outcomes after BCS (breast conserving surgery) with RT in this cohort of patients.

in research: abstract - MicroRNAs in Ovarian Cancer Biology and Therapy Resistance



Early evidence of prolonged disease stabilization in pre-treated patients suggests ENMD-1198 is worthy of additional investigation.



Abdominal Bloating: An Under-recognized Endometriosis Symptom



Thursday, January 21, 2010

Pleurodesis treatment : Cancer Research UK : CancerHelp UK



PatientView website



now accepting applications: Genetic Alliance



"We are now accepting applications for the Advocates Partnership Program at the American College of Medical Genetics (ACMG) Annual Clinical Genetics Meeting March 24-28 in Albuquerque, New Mexico."

ACOR - Association of Online Cancer Resources - Home Page



ACOR.org delivered 1,819,859 individual emails across the globe last week.

full access: Access to pain treatment as a human right



Omega-3 Fatty Acids for Neuropathic Pain: Case Series : The Clinical Journal of Pain



abstract/study of 5 patients

Jan 2009 full free access - Development of PARP inhibitors in oncology; Expert Opinion on Investigational Drugs + Expert Opinion



Note: highly technical but worth reviewing (BRCAness, sporadic, specific therapies (combination/single agent/+radiotherapy), those in clinical studies (Table 1),
differing cancers etc

Consumption of a Flaxseed-Rich Food Is Not More Effective Than a Placebo in Alleviating the Climacteric Symptoms of Postmenopausal Women - Journal of Nutrition