OVARIAN CANCER and US

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Monday, February 01, 2010

PLoS ONE: Risk of Ovarian Cancer and Inherited Variants in Relapse-Associated Genes



"...We previously reported results of tumor mRNA expression studies which suggested that altered expression of a particular set of genes predicted response to chemotherapy among women with advanced-stage high-grade epithelial ovarian cancer.......Conclusions: "Tumor studies can reveal novel genes worthy of follow-up for cancer susceptibility. Here, we found that inherited markers in the gene encoding MSL1, part of a complex that modifies the histone H4, may decrease risk of invasive serous ovarian cancer."

4th Familial Cancer Conference - Event - ESO




2007 (comparing cancer symptoms) - slide excerpt Benivegna/Pniauskas "Survivors' Debate: The Past Decade in Ovarian Cancer"




Has guideline development gone astray? Yes -- Grol 340: c306 -- BMJ



Has guideline development gone astray? No -- Gibbons et al. 340: c343 -- BMJ



Chemotherapy - MayoClinic - side effects information (general)



MicroRNAs in ovarian carcinomas -- Dahiya and Morin 17 (1): F77 -- Endocrine-Related Cancer



full free access: Duration and magnitude of the postoperative risk of venous thromboembolism in middle aged women: prospective cohort study



Note: the full access to this publication is available for free; professional comments included CONCLUSION: The risk of deep vein thrombosis and pulmonary embolism after surgery is substantially increased in the first 12 postoperative weeks, and varies considerably by type of surgery.

Ovarian Cancer: Your Guide to Taking Control



Reminder: Amazon has copies available

Journal of Experimental & Clinical Cancer Research | Full text | Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research



Note: there is a specific section on ovarian cancer

Background: Viscum album L. extracts (VAE, European mistletoe) are a widely used medicinal plant extract in gynaecological and breast-cancer treatment.  Conclusion: VAE shows some positive effects in breast and gynaecological cancer. More research into clinical efficacy is warranted.

Use of CT Scans Linked to Cancer Risk, Studies Say | netReturns | e-Newsletter



"There is considerable disagreement in the scientific community about the validity of these models," notes Rosaleen Parsons, M.D., chair of the department of diagnostic imaging at Fox Chase Cancer Center. "And some scientists believe the radiation dose from these CT scans may not lead to any increased risk of cancer."

In the second study, conducted at the University of California-San Francisco, researchers compared CT scan use at four San Francisco Bay area facilities. They found that the amount of radiation from a CT scan may be up to four times greater than estimated in previous studies. In addition, they noted significant differences among different institutions and, in some instances, within the same institution, when looking at the radiation dose associated with CT scans.

Sunday, January 31, 2010

Editorial: The heterogeneity of epithelial ovarian cancer. Getting it right David M. Gershenson



Editorial
The heterogeneity of epithelial ovarian cancer
Getting it right


David M. Gershenson, MD *
Department of Gynecologic Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
email: David M. Gershenson (DGERSHEN@mdanderson.org)

Abstract
Epithelial ovarian cancer is heterogeneous and comprises 4 major rare subtypes - mucinous, clear cell, low-grade serous, and endometrioid - all distinct from the more common high-grade serous carcinoma. Women with uncommon histotypes should be triaged to separate clinical trials.

Drug interactions with antiretrovirals and warfarin; Expert Opinion on Drug Safety



Pathways to the diagnosis of ovarian cancer in the UK: a cohort study in primary care BJOG



PD 0332991 in Treating Patients With Refractory Solid Tumors - Full Text View - ClinicalTrials.gov



PD 0332991 in Treating Patients With Refractory Solid Tumors - Full Text View - ClinicalTrials.gov

Communicate (animated film on you, your health, and the internet) - Denise Silber's eHealth




Search of: ovarian cancer | Open Studies | Adult - Results by Topic - ClinicalTrials.gov



Search results for Dietary Supplement - ovarian cancer:

Acidophilus 1 study
Arginine 1 study
Calciferol 4 studies
Cholecalciferol 3 studies
Citrate 13 studies
Folate 7 studies
Folic Acid 7 studies
Folinic Acid 8 studies
Orange 1 study
Tea 1 study
Tyrosine 1 study
Vitamin B9 7 studies
Vitamin D3 3 studies

Search of: ovarian cancer | Open Studies | Adult - Results by Topic - ClinicalTrials.gov



Search of: ovarian cancer | Open Studies | Adult - Results by Topic - ClinicalTrials.gov

Cancer patients 'must know rights' UK/Macmillan Cancer Centre



"Macmillan Cancer Support said that workers don't realise the Disability Discrimination Act (DDA) also protects cancer patients. A survey for the charity found more than half (53 per cent) of the 1,000 people questioned did not realise the act also applied to cancer patients."

A Physician's Perspective on Health 2.0 and Participatory Medicine



32 minute video

media article: The inherited malignancy of breast cancer (and ovarian cancer)



Note: good article, albeit complicated subject matter - excerpts of important information:

Soy product and isoflavone intake and breast cancer risk defined by hormone receptor status. 2009; Cancer Science



"he association between soy food consumption and breast cancer risk has been inconsistent. A hospital-based case–control study was conducted to assess the relationship between soy food intake and breast cancer risk according to the estrogen receptor (ER) and/or progesterone receptor (PR) status of breast cancer in Chinese women .....The protective effects of soy did not seem to differ by ER and PR breast cancer status."