abstract: Extrapancreatic Malignancies in Patients With Pancreatic Cancer: Epidemiology and Clinical Consequences

Abstract

Objectives:

To investigate the incidence, characteristics, and prognostic impact of prior extrapancreatic malignancies on patients with pancreatic cancer (PDAC).

Methods:

Records from 1733 patients who underwent surgery for PDAC were analyzed for the occurrence of prior extrapancreatic malignancies. Patients’ records showing extrapancreatic malignancies were then analyzed for tumor type, epidemiological data, risk factors, PDAC tumor stage, and long-term survival.

Results:

A total of 239 patients with PDAC (13.8%) had a history of 271 extrapancreatic tumors; 26 patients had a history of two pancreatic cancers, and 3 patients had 3 extrapancreatic cancers. The most common extrapancreatic tumors were breast cancer (56 patients) and prostate cancer (41 patients), followed by colorectal, reno/urothelial, and gynecologic tumors (39, 32, and 23 patients, respectively). No significant difference in overall survival was found between patients with PDAC with or without extrapancreatic malignancies.

Conclusions:

Pancreatic cancer is associated with extrapancreatic malignancies in a remarkable number of patients. A history of extrapancreatic malignancies does not influence prognosis and should not be an obstacle to a curative therapeutic approach. Surveillance of patients with extrapancreatic malignancies, especially breast, prostate, and colorectal cancer, could allow for earlier PDAC diagnosis and therefore improve prognosis of these patients.

abstract: Subspecialist training in surgical gynecological oncology in the nordic countries.

Establishing specialty jurisdictions in medicine: the case of American obstetrics and gynaecology 2011 - Sociology of Health & Illness

Abstract

The profession of medicine has evolved into an extremely specialised occupation.

Yet, recent research has neglected the intra-occupational processes influencing medical specialisation.

This article aims to correct this oversight.

It develops an historical account of intra-occupational factors influencing the decision to establish gynaecologic oncology as American ob/gyn’s surgical subspecialty in 1972. Working within the framework initially developed by Everett C. Hughes and his students, the article examines this development as the outcome of a three-party relationship among gynaecologic oncologists, American ob/gyns, and gynaecologic pelvic surgeons.

Aggressive movement by the gynaecologic pelvic surgeons challenging the established élite’s identity definition for the ob/gyn specialty helped spur official recognition of gynaecologic oncology, a less threatening subspecialty. The article draws theoretical implications from the case regarding the role of a threatening other in influencing the specialisation process.

index: Gynecologic Oncology V121 Issue1 April 2011

Note: this journal is by subscription ($$$)

Gynecologic Oncology Volume 121, Issue 1, Pages 1-244 (April 2011)

journal Gynecologic Oncology index of articles: Volume 121, Issue 1, Pages 1-244 (April 2011)

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articles 1 - 43

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Editorial Board   Page i  Show preview  |   Related articles  |  Related reference work articles

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New Biomarkers and Risk Predictors for Prevention and Early Detection of Gynecologic Cancers Special Section

Editorial

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Editorial   Page 1 Andrew Berchuck, Mark H. Einstein  Show preview  |   Related articles  |  Related reference work articles

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New Biomarkers and Risk Predictors for Prevention and Early Detection of Gynecologic Cancers: Articles

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A nomogram for estimating the probability of ovarian cancer  Original Research Article Pages 2-7 Jason A. Lachance, Asim F. Choudhri, Marc Sarti, Susan C. Modesitt, Amir A. Jazaeri, George J. Stukenborg  Show preview  |   Related articles  |  Related reference work articles

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Research Highlights

►This study presents a statistical model for measuring probability of ovarian cancer. ►Model includes age, ultrasound score, CA125 value, and nonlinearity adjustments. ►Excellent discrimination and calibration are obtained across the probability range.

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Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer  Original Research Article Pages 8-12 Jae Hong No, Yong-Tark Jeon, In-Ae Park, Yong-Beom Kim, Jae Weon Kim, Noh-Hyun Park, Soon-Beom Kang, Jae Yong Han, Jeong Mook Lim, Yong-Sang Song  Show preview  |   Related articles  |  Related reference work articles

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Research Highlights

► We investigated the expression of mTOR signaling molecules in ovarian cancer. ► Immunohistochemistry was done with antibodies against p-4EBP1, p-mTOR, and p-p70S6K. ► p-4EBP1 expression was associated with poor prognostic factors of ovarian cancer. ► p-4EBP1 overexpression may be a prognostic biomarker of ovarian cancer.

2011 journal issues - current content listings Jan/March 2011 including supplement (SGO meeting)

Articles in Press

	Volume 120 (2011)
		Volume 120, Issue 3 - selected pp. 317-492 (March 2011) Technologic Innovations and Novel Surgical Approaches for Patients with Gynecologic Malignancies
		Volume 120, Issue 2 pp. 165-316 (February 2011)
		Volume 120, Issue 1 pp. 1-164 (January 2011)
		Volume 120, Supplement 1 pp. S1-S150 (March 2011) ABSTRACTS PRESENTED FOR THE 42ND ANNUAL MEETING OF THE SOCIETY OF GYNECOLOGIC ONCOLOGISTS, ABSTRACTS PRESENTED FOR THE 42ND ANNUAL MEETING OF THE SOCIETY OF GYNECOLOGIC ONCOLOGISTS

Imedex: Great Debates & Updates in Gynecologic Malignancies April 9, 2011 New York, New York conference notice

(U.S.) Society of Gynecologic Oncologists Releases Data on the State of the Specialty

"SGO Practice Survey Task Force Chairman James Orr, MD, said in a news release, “The information in this report is a useful tool not only to current, practicing gynecologic oncologists with regard to how their practice composition relates to their peers, but also has important implications for individuals considering a career in this subspecialty, medical schools interested in creating a specialty program, and hospitals and health systems investigating the addition of specialized cancer care to their women's health care programs.”"

SGO E-Learning Center

SGO's 41st Annual Meeting on Women's Cancer Webcast Available Now!
FREE Introduction to Presidential Address, Cornelius Granai, MD
FREE Presidential Address, David Mutch, MD
FREE ACS Lectureship, Paul Goodfellow, PhD

Society of Gynecologic Oncologists Releases 'Gynecologic Oncology 2010: State of the Subspecialty' Survey Results -- CHICAGO, May 18 /PRNewswire-USNewswire/ --

Highlights from the survey include:

• A movement in the profession to younger-aged practitioners and a larger number of women entering the specialty;
• A shift away from private practice as the primary practice setting into salaried positions and an increase in group or multi-specialty practice from individual practice;
• An increase in the number of medical assistants, nurse practitioners and physician assistants employed in gynecologic oncology practices;
• A continued dedication to providing chemotherapy services to patients regardless of the changes in reimbursement rates, as well as the continuation of enrollment of patients into cooperative studies versus the more revenue neutral or positive industry-sponsored trials;
• The positive effect of caps on non-economic and total damages on the cost of medical liability/malpractice insurance; and the
• An overall willingness of gynecologic oncologists to accept/treat women with a gynecologic cancer without knowledge of insurance coverage and the preponderance of Medicare and Medicaid patients seen in a practice, versus private insurance.

The British Gynaecological Cancer Society Delphi Consultation Exercise on Expected Standards of Practice for Doctors Specializing in the Area of Gynecological Oncology

EPGM-Munich - Expert Practice in Gynecologic Oncology - free access

There are a number of slide presentations (free full access)