open access: JNCI - Predicting the Value of Indexing Symptoms for Ovarian Cancer

journal Gynecologic Oncology index of articles: Volume 121, Issue 1, Pages 1-244 (April 2011)

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articles 1 - 43

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New Biomarkers and Risk Predictors for Prevention and Early Detection of Gynecologic Cancers Special Section

Editorial

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Editorial   Page 1 Andrew Berchuck, Mark H. Einstein  Show preview  |   Related articles  |  Related reference work articles

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New Biomarkers and Risk Predictors for Prevention and Early Detection of Gynecologic Cancers: Articles

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A nomogram for estimating the probability of ovarian cancer  Original Research Article Pages 2-7 Jason A. Lachance, Asim F. Choudhri, Marc Sarti, Susan C. Modesitt, Amir A. Jazaeri, George J. Stukenborg  Show preview  |   Related articles  |  Related reference work articles

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Research Highlights

►This study presents a statistical model for measuring probability of ovarian cancer. ►Model includes age, ultrasound score, CA125 value, and nonlinearity adjustments. ►Excellent discrimination and calibration are obtained across the probability range.

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Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer  Original Research Article Pages 8-12 Jae Hong No, Yong-Tark Jeon, In-Ae Park, Yong-Beom Kim, Jae Weon Kim, Noh-Hyun Park, Soon-Beom Kang, Jae Yong Han, Jeong Mook Lim, Yong-Sang Song  Show preview  |   Related articles  |  Related reference work articles

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Research Highlights

► We investigated the expression of mTOR signaling molecules in ovarian cancer. ► Immunohistochemistry was done with antibodies against p-4EBP1, p-mTOR, and p-p70S6K. ► p-4EBP1 expression was associated with poor prognostic factors of ovarian cancer. ► p-4EBP1 overexpression may be a prognostic biomarker of ovarian cancer.

abstract: A new index of priority symptoms in advanced ovarian cancer

Note: advanced ovarian cancer study

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• Treatment of thromboembolism in cancer patients
  Marina Panova-Noeva, Anna Falanga

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Index of articles: Future Medicine - Biomarkers in Medicine - Vol. 4

Note: this journal requires subscription ($$$), abstracts available free

End of life 'quality' index | Open Medicine Blog

Integrative Cancer Therapies -- Table of Contents (June 2010, 9 [2])

Evaluation of the risk of malignancy index in daily clinical management of adnexal masses

Conclusions

"In our study population, introduction of the RMI would improve the management of adnexal masses, with a higher percentage of ovarian cancer patients that are operated by a gynecologic oncologist. At the same time, referral of patients with non-invasive (benign and borderline) lesions would be reduced."

Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer