Wednesday, February 03, 2010
Reuters Health Information (2010-02-02): Simple ovarian cysts not linked to cancer in postmenopausal women
"Women with and without simple cysts were at similar risk of invasive ovarian cancer after nearly 8 years of follow-up evaluation, the authors write. Furthermore, traditional ovarian cancer risk factors, such as increasing age, family history of breast or ovarian cancer, nulliparity, and infertility, were not associated with simple cysts. Finally, changes in average CA-125 were not correlated with increases in the number or progression of simple cysts.Thus, Dr. Greenlee and his group conclude, "Simple cysts are not likely cancer precursors or markers of increased risk and can be followed conservatively.""
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cancer
,
management
,
ovarian cancers
,
precursor
,
simple cysts
full free access: A novel germline PALB2 deletion in Polish breast and ovarian cancer patients
Conclusions:
The c.509_510delGA is a novel PALB2 mutation that increases the risk of familial breast cancer. Occurrence of the same PALB2 alteration in seven unrelated women suggests that c.509_510delGA (p.R170fs) is a recurrent mutation for Polish population.
Tuesday, February 02, 2010
Cochrane Symposium - Ottawa May 2010
Upcoming Cochrane Collaboration conference includes seminars for consumers/patients
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cochrane
,
conference
,
consumers
,
patients
Fertility-sparing surgery in young women with invasive epithelial ovarian cancer.
Note: this study also discusses tumour rupture/survival; the abstract does not include specific cell types, however, clear cell can be possibly presumed given the research data on Japanese women with clear cell ovarian cancer.
Clinical Activity of Gemcitabine Plus Pertuzumab in Platinum-Resistant Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Note: The response rates in this study either alone or in combination were low. The side effects appear to be understated (abstract).
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Gemcitabine
,
lancet oncology ovarian cancer detection study
,
Pertuzumab
Monday, February 01, 2010
Drugs A-Z List - A on RxList
This is a useful website for finding a lot of information relating to drugs, including chemotherapies. It includes drug interactions, warnings, generic names, pill identifier, medical dictionary etc. The website has been around for many years.
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dictionary
,
drug interactions
,
generic descriptors
,
information
,
pills
,
rxlist
,
warnings
full free access: from the series - the Art of Oncology : "Pessimism Is No Poison"
"....The fellow asked the oncologist why he was so pessimistic when talking with the patient. Why did he say things to make the patient and her husband cry? Shouldn't he have given the patient more hope? Would it not have been better for the patient to hear this dire news in chunks over the course of several clinic visits? After all, the patient was so young she may just beat the odds....."
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advanced cancer
,
communication
,
hope
,
Oncologist
,
prognostics
,
truth telling
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